He Yuan Li Ji

What are the reasons for the production of black glue worms

Pubtime：2024-01-31

View volume：141

There is still controversy over the reasons for the emergence of black glue worms, mainly including the following possibilities:

1. Microbial contamination: Black gum mites may be a type of microorganism such as bacteria, fungi, protozoa, etc. In the laboratory, cell cultures may be contaminated by microorganisms in the environment, which grow and reproduce under cultivation conditions, forming black gum worms.

2. Protein crystals in serum: Some people believe that black glue worms are protein crystals in serum. During cell culture, proteins in serum may crystallize and precipitate under certain conditions, forming black glue worms.

3. Cell death or debris: Black gum mites may also originate from debris after cell death. During the process of cell culture, fragments produced after cell death may accumulate in the culture medium, forming black glue worms.

4. Nanobacteria: Some researchers believe that black gum worms are a type of nanobacteria with special biological structures and growth characteristics, which make them appear as black granules under a microscope.

At present, there is no consensus on the source and nature of the black fungus, and further scientific research is needed to reveal its causes. In practical operation, in order to avoid the impact of black fungus on cell culture, it is necessary to strengthen the disinfection of laboratory environment, the handling and observation of cell culture materials, and adopt appropriate removal methods.

Recommended methods for removing black gum mites：EZ Black Gum Bug Removal Agent (Nabact Rid)

Previous：Instruction manual for eukaryotic cell transfection reagents, instructions for using high-efficiency transfection reagents

Next：Regarding the steps of cell cryopreservation and recovery, as well as the use of cell cryopreservation solution