Selected Literature | A comprehensive review of previous high scoring literature with an average impact factor of 8.098!
Another late spring is approaching, and over the years, He Yuan Li Ji has been continuously cultivating and refining, creating a good reputation with high quality and winning the trust of customers with strength.
According to recent statistics, literature indicating the use of Life iLab products showed that the highest impact factor in the previous period was 69.054, and the average impact factor was as high as 8.098! Thank you very much for your attention and support. He Yuan Liji will continue to assist the vast number of scientific researchers.
The following are some high scoring literature displays. For more literature, please refer toWeChat official accountorOfficial website
Partial display of high scoring literature
1、 Impact factor (IF)：69.504
title：Brown-fat-mediated tumour suppression by cold-altered global metabolism
periodical：Nature
Influencing factors：69.504
Publication date：2022-08-03
Units: Karolinska Institute in Sweden, Fudan University, Shandong University, Wenzhou Medical University, etc
DOI：https://www.nature.com/articles/s41586-022-05030-3
Quoting products | Item number | Specifications |
EZ ECL Pico chemiluminescence solution (ultra sensitive type) | AP34L024 | 100 mL |
AP34L025 | 500 mL |
Article Introduction: This work first discovered that cold exposure promotes glucose uptake in brown adipose tissue and inhibits glucose uptake in tumor cells, thereby inhibiting their growth. This discovery consolidates the important role of glucose metabolism in tumor development, reveals the impact of cold exposure on tumor tissue and its potential mechanisms, and proposes an anti-tumor "cold therapy".
二、Influencing factors（IF）：66.850
title：Large-Scale Multiplexed Mosaic CRISPR Perturbation in the Whole Organism
periodical：Cell
Influencing factors：66.850
Publication date：2022-07-22
Unit: School of Life Sciences, ShanghaiTech University
DOI：https://doi.org/10.1016/j.cell.2022.06.039
Quoting products | Item number | Specifications |
EZ Trans Cell Transfection Reagent (Efficient) | AC04L091 | 1mL |
AC04L092 | 50mL |
Article Introduction: This article reports a novel mouse gene targeting technique, iMAP (inducible Mosaic Animal for Turbulence), which rapidly identifies the basic functions of 90 genes in 39 tissues and constructs the world's first mouse "perturbation map".
3、 Impact factor (IF): 41.582
title：Local hyperthermia therapy induces browning of white fat and treats obesity
periodical：CellCover paper
Influencing factors：41.582
Publication date：2022-03-04
Unit: School of Life Sciences, East China Normal University, Sixth People's Hospital Affiliated to Shanghai Jiao Tong University
DOI：https://doi.org/10.1016/j.cell.2022.02.004
Quoting products | Item number | Specifications |
EZ Trans Cell Transfection Reagent (Efficient) | AC04L091 | 1mL |
AC04L092 | 50mL |
Article Introduction: This study innovatively found that in addition to cold stimulation, beige adipose tissue can sense local temperature and heat effects through HSF1 and activate thermogenesis, safely and effectively resisting and treating obesity and improving metabolic disorders such as insulin resistance and liver lipid deposition. In addition, this study is the first to discover the HSF1-A2B1 transcription axis at the genomic level, further improving the HSF1 metabolic regulatory network. And the association between HSF1 and metabolic traits has been clarified in a study of tens of thousands of people, providing new targets and strategies for intervening in obesity.
4、 Influencing factors（IF）：19.319
title：Dietary ketone body-escalated histone acetylation in megakaryocytes alleviates chemotherapy-induced thrombocytopenia
periodical：Science Translational Medicine封面论文
Influencing factors：19.319
Publication date：2022-11-30
Units: Fudan University, Longyan First Hospital Affiliated to Fujian Medical University, Tongji University
DOI：http://doi.org/10.1126/scitranslmed.abn9061
Quoting products | Item number | Specifications |
EZ PCR direct expansion mouse tail lysate | AN11L227 | 200 rxns |
AN11L228 | 500 rxns |
Article Introduction: This work first discovered that a ketogenic diet increases circulating β - OHB levels, and ketone bodies enter megakaryocytes in an MCT1 dependent manner, regulating platelet production gene expression through histone acetylation mechanism, thereby increasing platelet count. This discovery reveals the impact and mechanism of changes in megakaryocyte metabolic paradigms on platelet production, and proposes a safe and economical "ketogenic therapy" for treating CIT from the perspective of translational medicine.
5、Influencing factors（IF）：41.582
title：Broad neutralization of SARS-CoV-2 variants by an inhalable bispecific single-domain antibody
periodical：Cell
Influencing factors：41.582
Publication date：2022-03-09
Unit: Fudan University
DOI：https://doi.org/10.1016/j.cell.2022.03.009
Quoting products | Item number | Specifications |
EZ Trans Cell Transfection Reagent (Low Toxicity) | AC04L098 | 1mL |
AC04L099 | 50mL |
Article Introduction: This study demonstrates that this bispecific antibody can be effectively delivered to the lungs through inhalation administration and exhibits excellent neutralizing breadth and therapeutic effects in a mouse model infected with SARS-CoV-2. Importantly, this study also deciphered an uncommon and highly conserved hidden epitope within the spike protein trimer interface, which may have implications for designing broadly protected SARS-CoV-2 vaccines and therapies.
六、Influencing factors（IF）：38.104
title：SARS-CoV-2 Spike protein promotes vWF secretion and thrombosis via endothelial cytoskeleton-associated protein 4 (CKAP4)
periodical：Signal Transduction and Targeted Therapy
Influencing factors：38.104
Publication date：2022-09-22
Unit: Department of Physiology and Pathology, School of Basic Medicine, Tianjin Medical University
DOI：https://www.nature.com/articles/s41392-022-01183-9
Quoting products | Item number | Specifications |
Defined FBS (Foetal Bovine Serum) | AC03L055 | 500 mL |
Article Introduction: Many studies have shown that ACE2 is the main receptor for SARS-CoV-2 to enter cells, but ACE2 is lowly or not expressed in human endothelial cells. In addition, membrane proteomics did not detect the interaction between ACE2 and Spike protein, and DX600 did not inhibit Spike protein induced vWF secretion, further confirming that other potential receptors may mediate Spike protein related thrombosis. Researchers have found that endothelial cell CKAP4 can act as a novel Spike protein receptor, inducing vWF secretion and thrombus formation, providing a new target and treatment method for patients with thrombotic complications related to SARS-CoV-2.
七、other…
1、IF:27.287,Cell Metabolism,DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing, DOI:https://doi.org/10.1016/j.cmet.2021.09.008
2、IF:25.617,Cell Research,A novel STING Agonist-Adjuvanted Pan-Sarbecovirus Vaccine Elicits Potent and Durable Neutralizing Antibody and T Cell Responses in Mice, Rabbits and NHPs, DOI:https://doi.org/10.1038/s41422-022-00612-2
3、IF:19,J Clin Invest,Targeting fibrinogen-like protein 1 enhances immunotherapy in hepatocellular carcinoma, DOI:https://www.jci.org/articles/view/164528
4、IF:13.312,Cancer Research,TET2 suppresses VHL deficiency-driven clear cell renal cell carcinoma by inhibiting HIF signaling, DOI:https://doi.org/10.1158/0008-5472.CAN-21-3013
5、IF:13.3,Translational Research,Defining the Sensitivity Landscape of EGFR Variants to Tyrosine Kinase Inhibitors, DOI:https://doi.org/10.1016/j.trsl.2022.11.002
……
Back
