Bovine serum is an important natural culture medium in cell culture, containing abundant nutrients necessary for cell growth, and is commonly used for in vitro culture of animal cells. The main function of serum is to provide basic nutrients, hormones and various growth factors, binding proteins, contact promoting and stretching factors to prevent cell adhesion from mechanical damage, and to provide some protection to cells in culture.
There are many types of bovine serum, including fetal bovine serum, newborn bovine serum, calf serum, and adult bovine serum. So, what are the differences between bovine serum?
1. Blood collection age varies:
fetal bovine serumFoetal Bovine Serum, abbreviated as FBS, is fetal blood collected from 5-8 month old bovine embryos. At this time, the various organs of the fetal cow are in the stage of growth and differentiation, and the blood contains abundant growth and development factors, which are very suitable for the cultivation of various cells. Once the embryo develops completely, these factors will automatically disappear. Therefore, bovine embryos over 8 months of gestational age, which are close to full-term, cannot be used as raw materials for fetal bovine serum.
Newborn bovine serumNewborn Calf Serum (NBCS): collected from newborn cows within one day to one week of birth;
Calf serum（Calf Serum）：Taken from calves born 10-30 days ago;
Adult bovine serum（Adult Bovine Serum，abbreviationABS）：Serum was isolated from whole blood collected from adult cattle.
All serum must undergo strict quality control before leaving the factory, and a detailed "test report" should be attached, such as pH value, osmotic pressure, endotoxin, virus detection, cell growth promoting ability, sterility and other tests.
2. Different components and proportions:
The components and proportions of cytokines, adhesion promoting factors, hormones, and other active substances contained in the serum of these different cattle ages are different. Generally speaking, the younger the age of bovine serum, the better the cell culture effect. The cultivation effect of fetal bovine serum is better than that of newborn cattle, and because fetal cattle have not been breastfed, their IgG content is lower.
3. Different purposes and usage:
Determine different uses and usages based on the growth conditions required by the cells.
The above is an introduction to the difference between special grade fetal bovine serum and general serum. Let me explain it hereDefined FBS Living in a clean environment, their serum is isolated from the outside world. Premium fetal bovine serum is of the highest quality because fetal cows have not yet been exposed to the outside world. The antibodies, complement, and other harmful components contained in the serum are minimal. As long as the production process is scientific and standardized, its quality is definitely very good.
Recommended premium fetal bovine serum:Li Ji fetal bovine serum
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