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Why is the cell culture medium yellowish or purplish?

Pubtime:2024-07-02
View volume:124

The yellowing of cell culture medium is due to excessive cell density, which produces a large amount of acidic metabolic waste. When the pH increases, it causes phenol red discoloration, indicating insufficient cellular nutrition. The purple color of cell culture medium is due to the gradual overflow of CO2 from the culture medium, causing the medium to become increasingly alkaline and turn purple.

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