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Why do flocculent precipitates sometimes appear in serum? Do we need to remove it? How to remove it?

Pubtime：2024-03-14

View volume：244

There are various reasons that may lead to the formation of flocculent precipitates, and one of the most common reasons is the aggregation of lipoproteins during the melting process. This phenomenon generally does not affect product quality. Centrifuge at 400 g for 5 minutes, take the supernatant, and then filter. Choose the appropriate pore size of the filter membrane according to the needs, and the most commonly used is the 0.22 um PES material filter membrane. To avoid membrane blockage, it is recommended to centrifuge and add the supernatant to the culture medium for filtration instead of directly filtering the serum.

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