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Is L-glutamine important in cell culture? Is it unstable in solution?
L-glutamine is important in cell culture. After removing the amino group, L-glutamine can serve as an energy source for cultured cells, participate in protein synthesis and nucleic acid metabolism. L-glutamine degrades in solution after a period of time, but the exact degradation rate has not been conclusively determined. The degradation of L-glutamine leads to the formation of ammonia, which is toxic to some cells.